Our Research - Biomedical imaging
Overview
With vast experience in active micro-optics and optical sensing of, amongst others, acoustic behaviours, our research has moved into biomedical imaging applications underpined by this expertise. Both photoacoustic and fluorescence based imaging approaches are investigated, with our expertise in micro-optics, optical fibre sensors and optical ultrasound detection allowing the development of novel systems and multi-modal approaches to tackle application needs in clinical and biomedical research settings.
Funding sources
- EPSRC ("MEMS-enabled miniaturised multimodal microscopy through pulsed structured illumination")
- RAEng ("Miniaturised 3D-printed biomedical imaging system using optical MEMS")
- MRC ("Fast-tracking Health Innovation for NHS Scotland (MRC Confidence in Concept 2017)")
Current projects
Photoacoustic imaging
Mr Kusch, Mr Murdoch, Mr Donnachie, Dr Blue, Prof Uttamchandani, Dr Flockhart
In this project the development of photoacoustic imaging systems for investigations in cardiovascular and cancer research imaging questions is targeted. Combining the imaging systems with custom nanoparticle development and investigations in the fundamental imaging characteristics will allow impact on wideranging applications, anticipated to benefit clinicians in NHS research settings.
Project collaborators: Prof. Graham and Prof. Faulds, University of Strathclyde; Prof. Brunton, MRC Institute of Genetics & Molecular Medicine.
Miniaturised light sheet microscopy
Mr Bakas, Mr Donnachie, Prof Uttamchandani, Dr Bauer
The aim of this project is to develop miniaturised light sheet microscope systems that have full active control through micro-optic and MEMS components. Miniaturisation using cost-effective MEMS components will allow a deplyoment in wider research contexts, with an application in infectious disease research questions assessed during the project, specifically related to applications in developing countries.
Project collaborators: Prof. Toshiyoshi, University of Tokyo, Japan; Dr. Chakraborty and Dr. Dey, Indian Institute of Technology Gandhinagar, India.
Miniaturised super-resolution micoscopy
Dr Tinning, Mr Christopher, Prof Uttamchandani, Dr Bauer
The aim of this project is to create new super-resolution microscopy systems based on structured illumination techniques. The corner stone of these systems will be MEMS components, which allow all optical control and new approaches to generate the tailored illumination patterns required to circumvent the diffraction limit.
Project collaborators: Prof. Toshiyoshi, University of Tokyo, Japan;